There are also theme by theme differences in browser rendering. If you use Chrome and the "off" look is...off putting, you might want to do a little theme shopping and see if there's one that maintains the feel you want, but that looks better.
Almost freakishly, I periodically check posts with a lot of custom formatting from my site on Chrome, IE, Firefox, Safari AND Opera. (Yes, I have them all loaded on my box). And I've changed things to accommodate a single browser from time to time. I do not recommend this level of geekery, but with the proliferation of available themes you might be able to find a different one that renders more to your liking.